Legemiddel eller stoff som nedsetter aktiviteten av enzymet CYP1A2. Legemidler som tas samtidig og som nedbrytes av CYP1A2, kan dermed få en høyere konsentrasjon i kroppen slik at bivirkninger oppstår.Det er gjort flere studier på bruk av det kunstige hormonet i opptil seks måneder. De viser at bivirkninger kan omfatte hodepine og svimmelhet.H

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